CFTR modulators are one area of Cystic Fibrosis research. These are medications which help the underlying cause of CF, the CFTR channel. Correctors (help the CFTR to get to the surface) and potentiators (help the channel to open, such as Kalydeco) are examples of CFTR modulation.
There are multiple pharmaceutical companies working on CFTR modulation, including Vertex, N30, Pfizer, Genzyme, Galapagos, Proteostasis and Calista Therapeutics.
Please visit this page http://sixtyfiverosesblog.wordpress.com/future-medications/ for the updated information about future medications.